Sinus Infection Sinusitis Community Antibiotic Use Cdc Posted by elizabeth (south carolina) on 05/12/2016. i have c. diff and a chronic sinus infection. i have been in and out of doctors offices. sinus infection is only sensitive to iv antibiotics, yet i've been on lima different oral antibiotics since march 3rd because ent would not culture it for whatever reason. Chronic sinusitis occurs when the spaces inside your nose and head (sinuses) are swollen and inflamed for three months or longer, despite treatment. this common condition interferes with the way mucus normally drains, and makes your nose stuffy. See full list on mayoclinic. org. See a doctor if you have: 1. severe symptoms, such as severe headache or facial pain. 2. symptoms that get worse after initially improving. tiga. symptoms lasting more than 10 days without improvement. 4. fever longer than tiga-4 days. you should also seek medical care if you have had multiple sinus infections in the past year. this list is no...